Xiaflex is a new office based injection treatment for Peyronies disease.


Monthly injections into the penis are performed in combination with daily penile stretching performed by the patient. Up to four cycles of treatment may be required.  


I have been involved in trials of this medication. The effectiveness of Xiaflex has been proven in two large randomised trials. Typically there is a 30-40% improvement in bend. The side effect profile is favourable with most side effects being local and of mild to moderate severity.